Drug therapy for Mycetoma

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چکیده

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Mycetoma Medical Therapy

Medical treatment of mycetoma depends on its fungal or bacterial etiology. Clinically, these entities share similar features that can confuse diagnosis, causing a lack of therapeutic response due to inappropriate treatment. This review evaluates the response to available antimicrobial agents in actinomycetoma and the current status of antifungal drugs for treatment of eumycetoma.

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A 32-year-old woman from northeastern Brazil worked in farming and presented with a 6-year history of progressive swelling of the left foot. Swelling and sinuses draining purulent discharge with white grains ( Figure 1 ) were present. Potassium hydroxide preparation of drainage showed whiteyellowish nodules with fine filaments. Culture of the grains on Sabouraud agar and the casein hydrolysis t...

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Mycetoma

Mycetoma is a chronic infective condition of tropical and subtropical regions. It is commoner in males, especially those in their third or fourth decade who work on the land. The clinical triad of subcutaneous nodule, sinuses and discharge usually leads to diagnosis; the disease is commonly painless. Treatment is by extensive surgical excision of affected areas and may include limb amputation. ...

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ژورنال

عنوان ژورنال: Cochrane Database of Systematic Reviews

سال: 2018

ISSN: 1465-1858

DOI: 10.1002/14651858.cd013082